According to Jon’s research and findings, it’s not “work hardened” and adding the AF cam would not increase any risk to the crank, it only decreases it. If the crank already is fractured, there is no saving it though.
It’s not like a diff gear that does get work harden and create a pattern and changing that pattern can cause issues, noise or pre-mature wear. It’s like telling someone to NOT balance the rotating assembly on a used crank because it’s been ran that way for years. Balancing it only helps it
I personally don’t see a reason not to if it’s in the budget.