Travis. You can either run a welded tube or bolted on tube off the ped or machine a spot on the turbo housing itself like what Newly has. I originally welded the bung of the waste gate to the housing in that location about a year ago. It can crack from heat cycling if not recessed and sealed with a gasket. It's easy to machine it for a 38mm Tial and bolt it on. A stock cast exhaust housing has the meat for it.
Mike has a very good point on this for the Allison crowd that travels this route. I would find out the details on this from him.
Also keep in mind, the bigger the single is, the more rpm your going to need to spool it and where it likes to live. However the turbo side plays a huge part in this as well. The closer the turbine wheel is in exducer size to the inducer size of the compressor, the more easily it will surge (slight bark or reversing) with lighter drive pressures (partial throttle settings when climbing a grade or hill). A larger A/R incorporated to this equation makes it worse. However tighter ungated housings can make drive pressures spike when the Rs really climb. These are all general workings when you get into this field. Optimum set up really does require a drive pressure gauge and a turbo speed sensor to keep these in there best map. There are + & - to all this as well, but it's not rocket science either.