Not on a big tune, I always set it on a tow tune whenever I hooked up a trailer unless it was just getting moved in the yard. I dumped the compound kit because I kept blowing Intercooler boots while towing, cracked the stock Intercooler, and popped the HG's. Drive pressure was maxing out my pressure sensor at 100psi on the compounds also.
I have a 10k lb max weight bumper pull toy hauler 29' and took it from MN to CO for a track day and concert on the compounds, I lost about 5 silicone boots on that trip all on the driver side of the charge system. I was tired of workin on the truck so Jags recommended I swap to the 369 to simplify it and drop the drive pressure while still keeping the power and reliability.